|
rs397507444
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The risk observed for A1298C was 2.28 and 2.12 times higher in variants (AC + CC) of both DVT and CAD (OR = 2.28, 95%CI = 1.09-4.75 and OR = 2.12, 95%CI = 1.02-4.40, respectively).
|
31571711 |
2020 |
|
rs505151
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In CAD patients, the AG genotype of PSCK9 rs505151 is associated with diabetes and a positive family history of CAD.
|
30947598 |
2020 |
|
rs2228671
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We concluded that the heterozygosity in LDLR-rs72658855and rs2228671 and T allele in LDLR rs2228671are strongly associated with an increased susceptibility to coronary artery disease.
|
31613733 |
2020 |
|
rs1800566
|
|
|
0.020 |
GeneticVariation |
BEFREE |
NQO1 rs1800566 also associated with CAD, only in female.
|
31332605 |
2020 |
|
rs6850
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The CyPA platelet surface expression is associated with mortality whereas CyPA PPIA rs6850 is associated with recurrent MI in patients with symptomatic CAD.
|
31519036 |
2020 |
|
rs10159239
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Single Nucleotide Polymorphism rs10159239 was examined by logistic regression with known risk factors for Coronary artery disease and remained significant (0.035).
|
31639433 |
2020 |
|
rs6721961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, NRF2 rs6721961 associated with CAD and severity of coronary atherosclerosis.
|
31332605 |
2020 |
|
rs72658855
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A non-significant association was reported in recessive inheritance model for variant (CC+CT) vs. TT OR 0.56(0.16-1.95), P<0.36. and in dominant inheritance model for variant CC vs. (CT+TT) OR 2.8(1.07-7.34),P<0.032 .In case of allelic comparison, it was indicated that the LDLR rs2228671-T allele was associated with an increased risk of developing risk of CAD compared to C allele OR=2.4, 95% CI (1.05-5.64) P< 0.036 .Our findings showed that LDLR rs72658855 C>T gene variability is associated with an increased susceptibility to coronary artery disease in codominant inheritance model for variant CC vs. CT OR 1.7(1.1-2.6), P<0.015 and in dominant inheritance model for variant CC vs. (CT+TT) OR 1.66(1.07-2.58),P<0.0.02.
|
31613733 |
2020 |
|
rs756601757
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs972655070
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We speculate that this mutation [Arg196Trp] in the USF1 gene might be associated with FCHL and early-onset coronary heart disease in this family.
|
31725952 |
2020 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Further subgroup analyses showed that rs1333040, rs1333049 and rs2383207 polymorphisms were significantly correlated with the risk of CAD in East Asians, rs2383206 and rs10757274 polymorphisms were significantly correlated with the risk of CAD in West Asians, while rs2383206, rs10757274 and rs10757278 polymorphisms were significantly correlated with the risk of CAD in Caucasians.
|
30814313 |
2019 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
We genotyped the CAD-associated variants at the LPA (rs10455872) and 9p21 loci (rs1333049) in the GeneCAST (Genetics of Calcific Aortic STenosis) Consortium and conducted a meta-analysis for their association with AVS.
|
30482443 |
2019 |
|
rs1333049
|
|
|
0.900 |
GeneticVariation |
BEFREE |
Pooled overall analyses showed that rs1333040 (dominant model: P < 0.0001; recessive model: P < 0.0001; allele model: P < 0.0001), rs1333049 (dominant model: P = 0.02; allele model: P = 0.02) and rs2383207 (additive model: P = 0.004; allele model: P = 0.03) polymorphisms were significantly associated with the likelihood of CAD.
|
30387168 |
2019 |
|
rs4977574
|
|
|
0.890 |
GeneticVariation |
BEFREE |
The presence of rs4977574 G and rs1333040 T alleles and interaction may exist as environmental factors associated with lipid metabolism and might be responsible for the development of CAD in a Turkish Cypriot population.
|
30587704 |
2019 |
|
rs11556924
|
|
|
0.840 |
GeneticVariation |
BEFREE |
In the present study, we aimed to examine the role of two single-nucleotide polymorphisms (SNPs), rs3825807 and rs11556924, located in the ADAMTS7 and ZC3HC1 genes, respectively, associated with CAD in published GWASs in European populations and their possible contribution to the development of coronary atherosclerosis and cerebral LA atherosclerosis in a case-control study of an the Iranian population.
|
31679296 |
2019 |
|
rs10455872
|
|
|
0.770 |
GeneticVariation |
BEFREE |
We genotyped the CAD-associated variants at the LPA (rs10455872) and 9p21 loci (rs1333049) in the GeneCAST (Genetics of Calcific Aortic STenosis) Consortium and conducted a meta-analysis for their association with AVS.
|
30482443 |
2019 |
|
rs9349379
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Our study indicate that the PHACTR1 rs9349379 polymorphism is associated with the increased risk for CAD in the female Chinese Han population.
|
30777881 |
2019 |
|
rs9349379
|
|
|
0.760 |
GeneticVariation |
BEFREE |
Our meta-analysis suggested that rs9349379 polymorphism might affect individual susceptibility to CAD in both Caucasians and Asians.
|
31278837 |
2019 |
|
rs17465637
|
|
|
0.750 |
GeneticVariation |
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
rs1746048
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
rs9818870
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
rs11591147
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
rs12526453
|
|
|
0.730 |
GeneticVariation |
BEFREE |
In the present study, we have shown that the rs12526453 single-nucleotide polymorphism of the PHACTR1 gene is significantly associated with a 50% reduction in the odds of CAD events in FH subjects.
|
29784573 |
2019 |
|
rs7412
|
|
|
0.730 |
GeneticVariation |
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
rs2075291
|
|
|
0.720 |
GeneticVariation |
BEFREE |
A genetic variant c.553G > T (rs2075291) in the apolipoprotein A5 gene is associated with altered triglycerides levels in coronary artery disease (CAD) patients with lipid lowering drug.
|
30606120 |
2019 |